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Busulfan
This page contains brief details about the drug busulfan, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Busulfan is an anti-cancer medication that was approved to be used on 2 April 1999.
Mechanism of Action of Busulfan
Busulfan is an alkylating chemotherapeutic agent that disrupts DNA replication, which is essential for cell division. By inhibiting this process, it prevents tumor growth.
AVAILABLE BRANDS
Uses of Busulfan
- Hematopoietic progenitor cell transplantation
- Chronic myelogenous leukemia
- Polycythaemia vera (a type of cancer that causes an increase in red blood cells)
- Thrombocythemia (increased number of platelets in the blood)
- Myelofibrosis (type of blood cancer where scar tissues are formed in bone marrow)
- Hemoglobinopathies (a genetic disorder that produces abnormal hemoglobin)
- Brain Malignancies
Busulfan Drug administaration and Dosage available
Busulfan is available as a tablet that is to be swallowed whole with water. The available dose is 2mg.
Busulfan is an injection that is to be given only under the supervision of a qualified healthcare professional. The available dose is 6omg.
Warnings, Precautions and Side Effects of Busulfan
Warnings
Before starting treatment with Busulfan, inform your doctor if you have undergone radiotherapy recently, or have had gout. Report to your doctor if you have liver, kidney or lung conditions, or thalassemia before starting treatment with this medication.
Precautions
Both men and women are advised to take effective contraception while being treated with this medication. Busulfan is not be taken if you are pregnant or think you might be pregnant without consulting the doctor. Seek advice from your healthcare provider if you are already pregnant before starting treating treatment with this medication. Do not breast feed while being treated with Busulfan. Inform your doctor if you are lactose intolerant before starting treatment with this medication.
Side Effects
The common side effects that are likely to occur while you are on the treatment with Busulfan are thalassemia, skin rashes, hair loss, patches of dark skin, blood in urine, decrease in the number of blood cells and platelets, nausea and vomiting, jaundice, infertility, pneumonia Syndrome and itching.
Word Of Advice
Inform your doctor about any medications or supplements you are taking before starting treatment with Busulfan. If you experience itchy skin, fever, excessive sweating, chills, or difficulty breathing during or after the injection, notify your doctor immediately. Additionally, seek medical attention right away if you notice any signs of infection, fever, unexpected bruising, or bleeding. Busulfan may affect sperm and eggs, so discuss any fertility concerns with your doctor before using this medication.
Frequently Asked Question
No, you must not take Busulfan if you are intolerant to lactose or any other sugars as this medication contains lactose. Inform your doctor about being lactose intolerant before starting treatment with this medication.
No, busulfan is not be used during pregnancy without consulting a doctor. Inform your doctor if you are pregnant or think you might be pregnant before initiating treatment with tis medication. Seek advice from your healthcare provider if you are already pregnant before starting treating treatment with this medication.
Inform your doctor immediately if you notice symptoms of fever wile being treated with Busulfan.
Yes, Busulfan may have an effect on the sperms and eggs. Hence, seek advice you’re your doctor about any fertility concern you may have before using this medicine.
Yes, high doses of Busulfan can cause hair loss. Talk to your doctor about any hair loss concerns you may have.
Disclaimer
The drug information on this page is different from medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.