MEDICINES
PATIENT ASSISTANCE PROGRAMS
IMPORTED MEDICINES
CONTACT US
Upload
Introduction to Eylea 40mg Injection
Eylea 40mg/ml Injection comprises the active ingredient Aflibercept. It is employed to address eye conditions where impaired vision results from the development of abnormal blood vessels inside the eye. These conditions encompass wet age-related macular degeneration and diabetic macular edema. Research indicates that this medication significantly diminishes the risk of vision loss and enhances visual acuity in individuals with these conditions. It is generally well-tolerated by most patients, and the injection procedure is typically swift and minimally invasive.
It is advisable to steer clear of using Eylea 40mg/ml Injection if you have experienced severe hypersensitivity reactions to other anti-VEGF medications. Inform your physician about conditions such as glaucoma, a history of seeing floaters or flashes, and other illnesses before commencing Eylea 40mg/ml Injection. This medication should not be administered if there is an ongoing infection or inflammation around the eye. Additionally, it is crucial to inform your doctor if you have recently undergone eye surgery or have a planned procedure before initiating this medication.
Uses of Eylea 40mg Injection
- Neovascular (wet) age-related macular degeneration (wet AMD)
- Diabetic macular edema (DME)
- Myopic choroidal neovascularization (myopic CNV)
- Macular edema secondary to retinal vein occlusion
Therapeutic Effects of Eylea 40mg Injection
The mechanism of action of Eylea 40mg/ml Injection involves binding to and inhibiting the activity of vascular endothelial growth factor (VEGF). This protein is known to induce abnormal blood vessel growth and leakage in the eye, resulting in vision loss. Through its VEGF-inhibiting properties, this medication effectively reduces abnormal blood vessel growth and leakage, thereby improving vision in certain individuals with these eye conditions.
Interaction of Eylea 40mg Injection with other drugs
Notify your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Some medications may interact with Eylea 40mg/ml Injection, potentially reducing its effectiveness and leading to undesirable side effects.
More Information about Eylea 40mg Injection
- Store in a refrigerator at 2-8°C.
- Do not freeze.
- Protected from light.
- Keep it in its original packaging until it is ready to be used.
- Keep out of the reach of children and pets.
- Should be disposed of properly.
How to consume Eylea 40mg Injection
A medical professional will administer Eylea 40mg/ml Injection around the eye in a clinical setting. The dosage and infusion frequency will be adjusted based on the patient’s medical condition, age, weight, and other relevant factors. It is important for individuals not to double the dose to compensate for a missed one.
Safety Advices for Eylea 40mg Injection
Pregnancy
Limited information is available regarding the use of Eylea 40mg/ml Injection during pregnancy. Therefore, women who are pregnant or planning to become pregnant should consult their doctor before taking this medication.
Breast Feeding
It is uncertain whether Eylea 40mg/ml Injection is excreted in human milk. Therefore, if you are a breastfeeding mother, it is advisable to consult with a doctor before taking this medication.
Lungs
Individuals taking Aflibercept may encounter pulmonary adverse events, including symptoms like shortness of breath, coughing, and interstitial lung disease. Consequently, patients with pre-existing lung conditions such as COPD (chronic obstructive pulmonary disease) or asthma may face an elevated risk of experiencing pulmonary adverse events when undergoing this medication.
Liver
Eylea 40mg/ml Injection undergoes primary metabolism in the liver. Therefore, it is crucial to notify your healthcare provider if you have any liver problems or diseases. Additionally, this medication may elevate liver enzymes, which could indicate liver damage or inflammation. Patients using this medication should undergo regular blood tests to monitor their liver function.
Alcohol
While there is no known interaction between Eylea 40mg/ml Injection and alcohol, it’s important to note that excessive alcohol consumption can exacerbate liver-related side effects. Therefore, patients are advised to consult their doctor before consuming alcohol while undergoing this medication.
Driving
The use of Eylea 40mg/ml Injection may result in side effects like blurred vision, impacting a patient’s capacity to drive or operate heavy machinery. Individuals should refrain from driving or operating machinery until their vision returns to normal.
Side Effects of Eylea 40mg Injection
Similar to all medications, Eylea 40mg/ml Injection may induce certain side effects, although not every individual taking it will necessarily encounter them.
Serious:
- Blood clots or stroke
- Heart attack
- Severe bleeding or hemorrhage
- Gastrointestinal perforation (a hole in the stomach or intestine)
- Severe infections
- Hypertensive crisis (a sudden and severe increase in blood pressure
Common:
- Eye pain, irritation, or redness
- Blurred vision
- Increased tear production
- Sensitivity to light
- Headache
- High blood pressure
- Nasal congestion
- Nausea
- Vomiting
- Diarrhea
- Back pain
- Joint pain
Word of Advice
If you are undergoing Aflibercept treatment, it is vital to promptly inform your healthcare provider of any experienced side effects or concerns. For individuals who are pregnant, planning to conceive, or breastfeeding, it is crucial to consult with your healthcare provider to discuss the potential risks and benefits associated with the treatment. Patients with diabetic retinopathy should undergo close monitoring during the treatment period, as this medication has the potential to exacerbate the condition.
Should you encounter symptoms such as eye pain, escalating redness of the eye, diminished or blurry vision, or heightened sensitivity to light during your treatment, it is imperative to promptly notify your doctor. Implementing lifestyle changes, such as quitting smoking, maintaining a healthy weight, and adhering to a nutritious diet, can enhance overall health and diminish the risk of complications related to cancer. Emotional support from family, friends, or support groups can be beneficial in assisting cancer patients in navigating the challenges associated with their treatment.
FAQs
Q 1. How often will I need to receive Eylea 40mg/ml Injection?
The frequency of administering Eylea 40mg/ml Injection is contingent upon the particular condition being addressed and the patient’s response to the treatment. In the case of wet AMD, patients usually undergo an initial series of injections, followed by regular maintenance injections every 4 to 8 weeks.
Q 2. Will I still need to use my eyeglasses or contact lenses after receiving Eylea 40mg/ml Injection treatment?
Indeed, the administration of Eylea 40mg/ml Injection does not address refractive errors or cure any underlying eye conditions necessitating corrective lenses. Patients are advised to adhere to the use of any prescribed eyeglasses or contact lenses as directed by their healthcare provider.
Q 3. Can I receive local anesthesia before the Eylea 40mg/ml Injection?
Certainly, local anesthesia can be employed prior to administering Eylea 40mg/ml Injection to alleviate pain and discomfort during the procedure. The choice of anesthesia will be tailored to the patient’s requirements and the preferences of the healthcare provider.
Q 4. Can Eylea 40mg/ml Injection cause eye infections?
Though uncommon, there is a slight risk of eye infections linked to Eylea 40mg/ml Injection. Patients should promptly inform their healthcare provider of any symptoms indicative of an eye infection, such as redness, swelling, pain, or discharge.
Q 5. Can I take Eylea 40mg/ml Injection if I have high blood pressure?
Certainly, Eylea 40mg/ml Injection can be administered even if you have high blood pressure. However, it is crucial to communicate any existing medical conditions, including high blood pressure, to your healthcare provider before commencing treatment with Eylea 40mg/ml Injection. This is necessary because some patients may experience elevated blood pressure as a side effect of the medication.
Q 6. Can I take Eylea 40mg/ml Injection if I have a kidney problem?
Informing your healthcare provider about any kidney problems before initiating treatment with Eylea 40mg/ml Injection is crucial. Although Eylea 40mg/ml Injection is primarily intended for treating eye conditions and doesn’t directly impact the kidneys, it is eliminated from the body through the kidneys. Therefore, caution may be necessary in patients with impaired kidney function.
Fact Box of Eylea 40mg Injection
Molecule name: Aflibercept
Pharmacological class: VEGF Inhibitor
Therapeutic class: Anti-angiogenic agent
Indications:
1. Neovascular (wet) age-related macular degeneration (wet AMD)
2. Diabetic macular edema (DME)
3. Myopic choroidal neovascularization (myopic CNV)
4. Macular edema secondary to retinal vein occlusion
2. Diabetic macular edema (DME)
3. Myopic choroidal neovascularization (myopic CNV)
4. Macular edema secondary to retinal vein occlusion
References
- Katzung BG, Trevor AJ. Basic & Clinical Pharmacology, 14th Edition; 2018, 637-654
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, 13th edition, 2018, 1113-114
- Bayer AG, Electronic medicines compendium (EMC), [ Revised on Jan 2021] [ Accessed on 26th April 2023], https://www.medicines.org.uk/emc/files/pil.2879.pdf
- Regeneron Pharmaceuticals, Inc, US Food and Drug Administration, [ Revised on Nov 2011] [ Accessed on 26th April 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/125387lbl.pdf
Reviews
There are no reviews yet.