Introduction to Lupizotib 40mg Tablet
Lupizotib 40mg Tablet contain the active ingredient Cabozantinib and are classified as tyrosine kinase inhibitors. In adults, this medication is used to treat advanced kidney cancer and locally advanced or metastatic differentiated thyroid cancer. It is also indicated for liver cancer when Sorafenib is no longer effective. Typically, Cabozanib is used in combination with Nivolumab for advanced kidney cancer. It is not recommended for individuals under 18 years of age.
Do not take Lupizotib 40mg Tablet if you are allergic to Cabozantinib or any of its ingredients. Inform your doctor if you have liver disease, inflammatory bowel disease, high blood pressure, heart disease, or experience diarrhea. Notify your physician about any history of blood clots, significant bleeding, aneurysms, or tears in blood vessels. If you are pregnant, planning to become pregnant, or breastfeeding, discuss your options with your doctor and use effective contraception during and for four months after treatment. For any fertility concerns, consult your physician.
Uses of Lupizotib 40mg Tablet
- Advanced renal cell carcinoma
- Liver Cancer
- Differentiated thyroid cancer
Therapeutic Effects of Lupizotib 40mg Tablet
It acts against a protein called receptor tyrosine kinases and interferes with cell signaling, ultimately stopping the growth and spread of cancer cells. Lupizotib 40mg Tablet is indicated alone or in combination with Nivolumab.
Interaction of Lupizotib 40mg Tablet with other drugs
Inform your doctor about all prescribed medications, over-the-counter drugs, nutritional or vitamin supplements, and herbal products you are currently taking or have taken recently. Some medications, such as antibiotics, St. John’s Wort, and Aliskiren, may interact with Lupizotib 40mg Tablet and potentially cause unwanted side effects.
More Information about Lupizotib 40mg Tablet
- Keep out of sight and reach of pets and children
- Store protected from light at a temperature not exceeding 30°C.
How to consume Lupizotib 40mg Tablet
Take Lupizotib 40mg Tablet exactly as prescribed by your physician. Typically, this medication is taken once a day. Do not crush, chew, or open the tablets. Your doctor will determine the appropriate dosage and treatment duration based on factors such as age, body weight, and the condition being treated. Only discontinue use if directed by your doctor.
Safety Advices

Pregnancy
Unsafe to use during pregnancy as it may harm the unborn baby. Report to your doctor if you are pregnant or think you may be pregnant or planning for the pregnancy before starting the treatment.

Breast Feeding
Taking while breastfeeding may be unsafe because it may affect the child. Do not breastfeed for at least four months after the treatment. Therefore, talk with your doctor to get more information.

Lungs
It is unknown whether is safe to administer in patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.

Liver
Inform your physician if you have liver problems because should be used cautiously with this condition.

Alcohol
It is unknown whether consuming alcohol while taking a tablet is safe. Please speak with your physician.

Driving
While taking it is unsafe to drive or use machines because it may cause nausea, changes in vision, vomiting, etc. Talk to your doctor for more information.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Gastrointestinal perforation
- Severe or uncontrollable bleeding
- Shortness of breath
- Nonhealing wound
- Pain in the mouth, jaw/teeth, hand, feet,
- Loss of consciousness,
- Drowsy
- Swelling or sores in the mouth
- Blood vomiting
- Black stools
- Blood in urine
- Headache
- Coughing blood
Common
- Dehydration
- Difficulty swallowing
- Ringing in the ears
- Blood clots in the veins
- Fluctuation in the blood sugar levels
- The lower level of albumin
- Electrolyte imbalance
- Increased levels of liver enzymes
- Elevated cholesterol levels in the blood
- Hair loss
- Changes in hair color
- Muscle spasm
- Skin thickening
- Dry skin
- Itching
- Protein in urine
Word of Advice
Oral contraception may be ineffective while under the treatment of Discuss effective contraception methods with your doctor, along with fertility concerns. Inform your doctor if you have a thyroid problem; thyroid function should be monitored regularly before taking this medicine. Notify your doctor if your face gets colder or tired more commonly or if your voice deepens while taking this medicine. Do not stop the medicine until your doctor advises. Notify your doctor if you experience any serious side effects. You are doctor may change your dose or stop the treatment. Your doctor will inform you if you need any dose adjustments. This medicine is not recommended for children or adolescents.
FAQs
Q 1. Can Lupizotib 40mg Tablet cause a lower level of albumin?
One of the common side effects of Cazanat 40mg Tablet is the lower level of albumin. If you experience any side, contact your physician immediately.
Q 2. Why is it recommended to use effective contraception during the treatment of Lupizotib 40mg Tablet?
To avoid unwanted pregnancy, it is advised to use effective contraception. Oral contraception may be ineffective, so it is better to discuss effective contraception with your doctor.
Q 3. Why is liver enzyme getting elevated during treatment with Lupizotib 40mg Tablet?
The reason for this elevation is not completely understood, but it is thought to be related to the drug’s effects on certain enzymes involved in liver function. The elevation in liver enzymes is generally mild and temporary and typically resolves on its own or with a dose adjustment of the Lupizotib 40mg Tablet.
Fact Box
Molecule Name: Cabozantinib
Pharmacological class: Tyrosine kinase inhibitor
Therapeutic class: Antineoplastics
Indications:
1. Advanced renal cell carcinoma
2. Liver Cancer
3. Differentiated thyroid cancer
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