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Introduction to Casirivimab Imdevimab (Regn-Cov2) Injection
Casirivimab Imdevimab (Regn-Cov2) Injection contains the active ingredients Casirivimab and Imdevimab, which are monoclonal antibodies. This injection is used to treat patients with confirmed acute COVID-19 infection and is also indicated for the prevention of acute COVID-19 infection. COVID-19, caused by the coronavirus, is transmitted through contact with an infected person.
Do not use Casirivimab Imdevimab (Regn-Cov2) Injection if you are allergic to Casirivimab, Imdevimab, or any other components of the medication. This medicine may cause allergic reactions following infusion or injection; if you experience any infusion-related reactions, notify your physician immediately. Before receiving this injection, inform your doctor if you have been vaccinated against COVID-19. Additionally, if you are pregnant or breastfeeding, consult your doctor before starting treatment.
Uses of Casirivimab Imdevimab (Regn-Cov2) Injection
- Treat and prevent acute COVID-19 infection.
Therapeutic Effects of Casirivimab Imdevimab (Regn-Cov2) Injection
Casirivimab Imdevimab (Regn-Cov2) Injection are two recombinant human monoclonal antibodies that attach to a protein on the surface of the coronavirus called the ‘spike protein.’ This stops the virus from getting into your cells and causing an infection. They block the receptor binding domain (RBD) to the ACE2 receptor and prevent viral attachment to host cells. This can help your body to overcome the virus infection and may help you get better faster.
Interaction of Casirivimab Imdevimab (Regn-Cov2) Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional, vitamin supplements, and herbal products. Certain medications interact with Casirivimab Imdevimab (Regn-Cov2) Injection, reducing their effectiveness by causing undesirable side effects.
More Information about Casirivimab Imdevimab (Regn-Cov2) Injection
- Store in a refrigerator (2°C to 8°C)
- Do not freeze
- Protect the medicine from light and excessive moisture.
- Keep the medicine out of reach of children and pets
- If you missed the dosing schedule, inform your healthcare professional immediately and reschedule.
How to consume Casirivimab Imdevimab (Regn-Cov2) Injection
Casirivimab Imdevimab (Regn-Cov2) Injection is given as an infusion into your vein that lasts for 20 to 30 minutes, or it can be given as a subcutaneous (under the skin) injection. This injection will be given to you by a doctor or nurse who is experienced in the use of this type of treatment. They will monitor you closely while you are being given this medicine. Do not self-administer this medicine.
Safety Advices
Pregnancy
There is limited information on the safety of Injection during pregnancy. Inform your physician if you are pregnant, suspecting, or planning for pregnancy.
Breast Feeding
There is limited information on the safety of Injection during breastfeeding. Inform your physician if you are pregnant, suspecting, or planning for pregnancy.
Lungs
It is unknown whether Injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
There is limited information available on the use of Injection in patients with liver diseases. Inform your physician if you have any liver problems, before initiating the treatment.
Alcohol
It is unknown whether it is safe to consume alcohol with Injection. Inform your physician if you are a chronic drinker.
Driving
Injection does not affect your ability to drive and operate heavy machinery. Inform your physician if you face any symptoms that alter your concentration.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Hypersensitivity reaction
- Infusion reaction
Word of Advice
Self isolate and use infection control measures (eg, wearing mask, social distancing, avoid sharing personal items, clean and disinfecting “high touch” surfaces, and frequent handwashing). The most common side effects may include infusion-related reactions such as swelling in the hands, face, and feet, skin rash, breathing difficulties, cough, abdominal pain, and chest pain. Injection site reactions like swelling and redness at the injection site can also occur.
FAQs
Q 1. How effective is Casirivimab Imdevimab (Regn-Cov2) Injection in treating COVID-19?
Clinical studies have shown that Casirivimab Imdevimab (Regn-Cov2) Injection can significantly reduce the risk of hospitalization or death in high-risk individuals with COVID-19. However, the effectiveness may vary depending on individual factors, including the illness’s severity and specific variants of the virus.
Q 2. Can Casirivimab Imdevimab (Regn-Cov2) Injection be used in combination with other COVID-19 treatments?
Casirivimab Imdevimab (Regn-Cov2) Injection can be used alone or in combination with other COVID-19 treatments as determined by healthcare professionals. It is important to consult with healthcare providers to ensure proper coordination of treatments and minimize any potential interactions.
Q 3. How soon after testing positive for COVID-19 should Casirivimab Imdevimab (Regn-Cov2) Injection be administered?
Casirivimab Imdevimab (Regn-Cov2) Injection is most effective when administered early after testing positive for COVID-19, ideally within 10 days of symptom onset. Early treatment helps reduce the severity of illness and the risk of hospitalization.
Fact Box
Molecule name: Casirivimab + Imdevimab
Pharmacological class: Monoclonal Antibodies
Therapeutic class: Antiviral
Indications: Treat and prevent acute COVID-19 infection
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