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Introduction to Crizalk 250mg Capsule
Crizalk 250 mg contains the active ingredient Crizotinib, an antineoplastic agent in the tyrosine kinase inhibitor class. It is prescribed for treating patients with ALK-positive non-small cell lung cancer (NSCLC) that is locally advanced or has metastasized (spread to other parts of the body). Avoid taking Crizalk if you are allergic to Crizotinib or any other components of the medication. Before starting treatment, inform your doctor if you have any history of kidney, stomach, heart, or liver issues.
Be sure to notify your doctor if you have low white blood cell counts, abnormal ECG readings, vision problems, or are taking any other medications. If you are planning to become pregnant or suspect you may be, consult your doctor immediately. Discuss effective contraception options, as oral contraceptives are not effective with Crizalk; use reliable birth control throughout treatment and for at least 90 days after completing therapy. Speak to your doctor if you have any fertility-related concerns. Crizalk is not recommended for patients under 18. To protect your skin, use sunscreen and wear protective clothing to prevent sunburn.
Uses of Crizalk 250mg Capsule
- Anaplastic lymphoma kinase (ALK) positive non-small cell lung cancer (NSCLC)
Therapeutic Effects of Crizalk 250mg Capsule
Crizotinib is a tyrosine kinase inhibitor that works by blocking the activity of the anaplastic lymphoma kinase (ALK) protein. It specifically targets the abnormal protein and blocks its activity, slowing down or stopping the growth and spread of cancer cells.
Interaction of Crizalk 250mg Capsule with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, recent vaccinations, nutritional and vitamin supplements, and herbal products. Certain medications such as Erythromycin, Diltiazem, Verapamil, and other medications may interact with Crizalk 250mg and reduce its effectiveness by causing undesirable side effects.
More Information about Crizalk 250mg Capsule
- Store at room temperature (15-30˚C) in the original container
- Keep this medicine out of the sight and reach of children.
How to consume Crizalk 250mg Capsule
Take the Crizalk 250mg capsules at about the same time each day. The recommended dose is one capsule of 250 mg taken orally twice daily. Swallow the capsules whole and do not crush, chew, dissolve, or open the capsules. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.
Safety Advices
Pregnancy
Crizalk 250mg capsule medicine is unsafe to use during pregnancy. Hence, check with your physician before taking this medicine if you are pregnant or think you might be pregnant.
Breast Feeding
It is unsafe to breastfeed while taking Crizalk 250mg capsule because it can cause toxicity to the baby. Consult your physician for more information.
Lungs
Inform your doctor immediately if you experience any symptoms like lung inflammation, difficulties in breathing, cough with or without mucous, or even fever while taking Crizalk 250mg capsule.
Liver
Inform your physician about any underlying liver disorders before taking Crizalk 250mg capsule, as this medication should be used with caution in liver disease patients. Consult your physician before taking this medicine.
Alcohol
It is not known whether it is safe to consume alcohol with Crizalk 250mg capsule. Please consult your doctor.
Driving
It is unsafe to drive while taking Crizalk 250mg capsule because this medicine might cause dizziness and tiredness, so avoid driving and operating machinery during this treatment.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Pain on the right of the stomach
- Partial or full loss of vision
- Lowered WBC
- Low heart rate.
- Swelling of the lungs.
- Breathlessness
- Cough with or without mucus
Common
- Sensitivity to sunlight.
- Diarrhea
- Fever
- Constipation
- Nausea
- Increased liver enzymes
- Decreased appetite Tiredness (fatigue)
- Dizziness
- Neuropathy (weakness, tingling, or numbness in the nerve)
- Dysgeusia ( taste disorder)
- Hypophosphataemia (low levels of phosphate in the blood)
Word of Advice
Inform your doctor if you notice a reduced number of white blood cells (Neutropenia) and RBC because the reduction in red blood cells can make the skin pale and cause weakness or breathlessness (Anaemia) and low white cell count (Leucopenia). Your doctor may perform an electrocardiogram to check your heart functioning level. It is important to take a Crizalk 250mg capsule every day as long as your doctor prescribes it. Avoid spending much time in sunlight because it can make your skin sensitive to the sun (photosensitivity), and you may burn more easily. Inform your doctor if you notice a slower heart rate or stomach problems like perforation and ankle swelling.
FAQs
Q 1. Does Crizalk 250mg capsule cure cancer?
Crizalk 250mg capsule is not a cure for cancer, but it can help to slow down or stop the growth and spread of cancer cells, improving the overall survival and quality of life of patients with certain types of cancer.
Q 2. What should I do if I miss a dose of Crizalk 250mg capsule?
If you miss a dose of Crizalk 250mg capsule, you should take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Q 3. What should I tell my doctor before taking Crizalk 250mg capsule?
Before taking Crizalk 250mg capsule, you should tell your doctor if you have liver or kidney problems, a history of heart disease, or are pregnant or planning to become pregnant.
Fact Box
Molecule name: Crizotinib
Pharmacological class: Tyrosine kinase inhibitors
Therapeutic class: Antineoplastic drug
Indication:
Anaplastic lymphoma kinase (ALK) positive non-small cell lung cancer (NSCLC)
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