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Introduction to Halkeran 5mg Tablet
Halkeran 5mg Tablet contain the active ingredient chlorambucil, an anti-cancer medication that belongs to the class of alkylating agents. It is primarily used to treat Hodgkin’s disease and non-Hodgkin’s lymphoma, which are cancers originating from cells in the lymphatic system. Additionally, it is prescribed for chronic lymphocytic leukemia (a type of white blood cell cancer where the bone marrow produces an excessive number of abnormal cells) and Waldenstrom’s macroglobulinemia (a rare lymphoma characterized by an uncontrolled increase in B-cells, leading to the release of an abnormal protein into the blood).
Do not use this medication if you are allergic to Halkeran 5mg Tablet or any of its ingredients. Be sure to inform your physician about your recent vaccination history, as well as any liver or kidney issues, or history of seizures. Also, let your doctor know if you have undergone radiotherapy or chemotherapy recently. Long-term use of this medication may increase the risk of developing secondary blood cancer.
Uses of Halkeran 5mg Tablet
- Hodgkin’s Lymphoma
- Non-Hodgkin’s Lymphoma.
- Chronic lymphocytic leukemia
- Waldenstrom’s macroglobulinemia
Therapeutic Effects of Halkeran 5mg Tablet
Halkeran 5mg Tablet is an aromatic nitrogen mustard derivative and alkylating agent that interferes with DNA replication. It also induces cellular apoptosis by accumulating protein cytosolic p53 and activating BAX, a cell death promoter. It works by reducing the number of abnormal cells your body makes.
Interaction of Halkeran 5mg Tablet with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, vaccinations, nutritional and vitamin supplements, and herbal products. Certain medications interact with Halkeran 5mg Tablet and reduce its effectiveness by causing undesirable side effects.
More Information about Halkeran 5mg Tablet
- Store in a refrigerator (2 and 8°C).
- Protect the medicine from light and excessive moisture.
- Keep the medicine out of reach of children and pets
- If you forgot to take the tablet, take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.
How to consume Halkeran 5mg Tablet
It is an orally available prescription drug. Your doctor will decide the dose and duration of Halkeran 5mg Tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet daily on an empty stomach at least one hour before meals or three hours after meals. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water.
Safety Advices
Pregnancy
Do not take tablet if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment. Use effective contraception during the treatment.
Breast Feeding
Breastfeeding is not recommended in patients taking tablet because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
Lungs
It is unknown whether tablet is safe to be administered in patients with lung diseases. Inform your physician if you have any lung diseases before initiating the therapy.
Liver
It is unknown whether tablet is safe to be administered in patients with liver diseases. Inform your physician if you have any liver diseases before initiating the therapy.
Alcohol
It is not known whether it is safe to consume alcohol with tablet. Please consult your doctor.
Driving
It is not known whether tablet alters the ability to drive or operate heavy machinery. If you feel dizzy or sleepy, avoid driving and consult your doctor.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Anemia
- Decreased platelet count
- Decreased white blood cells
Common
- Severe skin reactions
- Liver toxicity
- Hypersensitivity reaction
- Seizure
- Hallucinations
- Infertility
- Lung problems
Word of Advice
Inform your physician if you have bone marrow problems, head injury, type of infection, or a history of seizures. This medicine makes you bleed, bruise or get infections more easily. Take precautions to prevent illness and injury. If you vomit after taking the medicine, do not take an extra dose. Take your next dose at the regular time. Do not stop taking this medicine without talking to your doctor. Your doctor may do lab tests to check the therapy’s effectiveness or monitor the unwanted side effects.
FAQs
Q 1. What happens if Halkeran 5mg Tablet is not refrigerated?
The stability and effectiveness of the tablets will reduce if it is not refrigerated properly. Store the tablet at 2°C and 8°C.
Q 2. Can Halkeran 5mg Tablet be given on an empty stomach?
Take this medication on an empty stomach at least 1 hour before or 2 hours after food. If you miss a dose, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double dose.
Q 3. Can Halkeran 5mg Tablet cause bleeding?
Yes, Halkeran 5mg Tablet can make you bleed or bruise. Take necessary precautions to prevent injury.
Fact Box
Molecule name: Chlorambucil
Pharmacological class: Alkylating agent
Therapeutic class: Anti-cancer
Indications:
1. Hodgkin's Lymphoma
2. Non-Hodgkin’s Lymphoma.
3. Chronic lymphocytic leukemia
4. Waldenstrom's macroglobulinemia
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