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Introduction to Isotret 20mg Capsule
The Isotret 20mg capsule is an antineoplastic medication containing Tretinoin as its active ingredient. Classified within the retinoid medication class, akin to vitamin A, it is employed in the treatment of acute promyelocytic leukemia. This medication works by inhibiting the proliferation of abnormal blood cells, contributing to the management of this specific blood disorder.
If you have an allergy to Tretinoin or any other components of this medication, or if you are currently using medications such as vitamin A, tetracyclines, or retinoids (Isotretinoin, Acitretin, Tazarotene), refrain from taking this medicine. Additionally, as this medication contains soya bean oil, it is advisable to avoid it if you have a sensitivity to peanuts or soya. It is crucial to discuss with your doctor any other health conditions you may have or if you have a history of mental health issues like depression, mood changes, or aggressive behavior, as the use of this medicine may impact your mood.
Prior to taking this medication, communicate with your healthcare provider if you are intending to become pregnant, already pregnant, or breastfeeding. It is crucial to employ effective contraception even after discontinuing the medicine for one month. Inform your doctor of any allergies or sugar intolerance, as this medication contains sorbitol. Limited information is available regarding the use of this medicine in children; consult your doctor for further details. Promptly report to your doctor if you encounter any side effects, such as fever, chest or back pain, difficulty breathing, or fever.
Uses of Isotret 20mg Capsule
- Acute promyelocytic leukemia
Therapeutic Effects of Isotret 20mg Capsule
Isotret 20mg capsule binds to the fusion protein and breaks down the protein, making the immature blood cells differentiate into mature white blood cells (WBC). This helps restore normal blood cell production and reduces the number of abnormal cells present in blood and bone marrow.
Interaction of Isotret 20mg Capsule with other drugs
Notify your doctor of any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you are currently taking or have taken prior to initiating treatment. Some medications, including low-dose progestogens (birth control pills), Isotretinoin, Acitretin, Tazarotene, and others, may interact with Isotret 20mg capsule, potentially leading to undesirable side effects.
More Information about Isotret 20mg Capsule
- Keep out of sight and reach of pets and children
- Store protected from light at a temperature not exceeding 30°C.
- Isotret 20mg capsule treatment can take three months or longer. Do not stop until your doctor advises.
How to consume Isotret 20mg Capsule
Follow your physician’s instructions when taking Isotret 20mg capsule. Do not crush, chew, or open the medication. The appropriate dosage and duration will be determined by your doctor based on factors such as age, body weight, and the specific disease condition. Only discontinue Isotret 20mg capsule if your doctor advises you to do so.
Safety Advices for Isotret 20mg Capsule
Pregnancy
Isotret 20mg capsule is not recommended during pregnancy as it may pose a risk to the unborn baby. Inform your doctor if you are pregnant, suspect pregnancy, or are planning to become pregnant before initiating the treatment.
Breast Feeding
Using Isotret 20mg capsule while breastfeeding may pose risks as it could potentially affect the child. It is advisable not to breastfeed for at least four months after completing the treatment. Consult with your doctor for more detailed information.
Lungs
The safety of Isotret 20mg capsule in patients with lung problems is uncertain. Notify your doctor if you have any lung disease before initiating the treatment. Seek medical attention if you encounter difficulties in breathing or experience any symptoms related to lung issues.
Liver
Limited information is accessible regarding the usage of Isotret 20mg capsule in patients with liver conditions. Consequently, the safety of the medication for individuals with liver problems is uncertain. Inform your physician about any liver disease before commencing the treatment, and seek medical advice if you encounter symptoms related to liver issues.
Alcohol
The safety of consuming alcohol while taking Isotret 20mg capsule is uncertain. It is recommended to consult with your physician for guidance.
Driving
Engaging in activities such as driving or operating machinery is not advisable while taking Isotret 20mg capsule, as it may lead to dizziness or severe headaches. Consult with your doctor for further information.
Side Effects of Isotret 20mg Capsule
Side Effects of Isotret 20mg Capsule
Serious:
- Difficulty in breathing
- Fever Coughing
- Dizziness
- Pain in chest and abdomen
- Severe headache
- Severe stomach pain that spread to back (the sign of pancreatitis)
- Dark lumpy makings on the skin
- Swelling in leg
- Double vision
- Ringing in the ear and headache
- Sudden migraine
Common:
- Hair loss
- Irregular heartbeat
- Joint pain
- Bone pain
- Skin rashes, itching, redness, inflammation
- Dryness in skin, mouth, nose
- Respiratory failure
- Unusual sweating
- Mood swings
- Numbness or tingling on hands or feet
- Constipation
- High levels of blood creatinine or blood fats
Word of Advice
Report any side effects you experience to your doctor; they may adjust the dosage of Isotret 20mg capsule or prescribe additional medication to alleviate side effects. Even if you haven’t observed changes in your mood and behavior, it is recommended to inform your friends and family as this medication may impact mood and behavior. Discuss effective contraception methods with your doctor to prevent pregnancy. Women should undergo pregnancy tests every four months during treatment. If you become pregnant, notify your doctor promptly for appropriate guidance. Only take other medications if prescribed by your doctor.
FAQs
Q 1. Why use effective contraception during the treatment of Isotret 20mg capsule?
To prevent unintended pregnancy, it is recommended to use reliable contraception methods. If you become pregnant while using Isotret 20mg capsule, notify your doctor promptly for appropriate guidance and treatment. Additionally, discuss effective contraception options with your doctor.
Q 2. What are the different forms of Isotret 20mg capsule available?
Isotret 20mg capsule is mainly accessible in two formulations: topical creams and gels, as well as oral capsules.
Q 3. Do Isotret 20mg capsule cream and capsules have the same medical use and impact?
No, the Isotret 20mg capsule cream is applied topically to address skin conditions like acne and rashes. In contrast, the capsule is administered to decrease the quantity of abnormal cells in the body.
Q 4. Should I double-dose Isotret 20mg capsule if I missed the dose?
No, it is not recommended to double dose Isotret 20mg capsule even if you miss your regular dose. If you forget to take a dose, take one as soon as you remember. If you accidentally take a double dose, promptly contact your doctor for guidance.
Q 5. Is that okay to take Isotret 20mg capsule for kidney disease?
Limited information is accessible regarding the use of Isotret 20mg capsule in patients with kidney conditions. Therefore, it is recommended to inform your doctor about any history of kidney issues before initiating the treatment.
Fact Box of Neomol 80mg Injection
Molecule Name: Tretinoin
Pharmacological class: Retinoids
Therapeutic class: Anti-neoplastics
Indications: Acute-promyelocytic leukemia
References
- Neon Healthcare Ltd, Electronic Medicines Compendium(EMC), [Revised on Dec 2020], [Accessed on 26th April 2023], Tretinoin 10mg soft capsules – Patient Information Leaflet (PIL) – (emc) (medicines.org.uk)
- Glenmark Pharmaceuticals, [Revised on Dec 2018] [Accessed on 26th April 2023], https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=264138c1-9e5f-45ef-be87-79ca97c989d9&type=display
- KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.
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