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Introduction to Leucovorin Calcium 15mg Injection
Leucovorin Calcium 15mg Injection contains the active ingredient Leucovorin calcium, a substance chemically related to folic acid, and is classified as a folic acid analog. It is primarily used to prevent the harmful effects of methotrexate during the treatment of certain cancers. Additionally, it is used to treat individuals who have accidentally overdosed on methotrexate or similar medications. is also used in combination with other anticancer drugs to treat colorectal cancer, which begins in the colon or rectum, and to treat anemia caused by low folic acid levels.
Do not use Leucovorin Calcium 15mg Injection if you are allergic to calcium folinate, or any other components of this medication. It is also contraindicated in certain types of anemia (such as pernicious anemia or megaloblastic anemia) where there is a deficiency of vitamin B12. Before starting treatment, inform your physician if you have any form of anemia, or if you have kidney, heart, or liver issues. Also, let your physician know if you are taking medications for seizures. Seek immediate medical attention if you experience symptoms such as wheezing, difficulty breathing, skin rash, itching, hives, or swelling of the lips, face, or tongue.
Uses of Leucovorin Calcium 15mg Injection
- Methotrexate overdose and toxicity
- Prevent the harmful effects of methotrexate or similar medications
- Colorectal cancer
- Anemia
Therapeutic Effects of Leucovorin Calcium 15mg Injection
Leucovorin Calcium 15mg Injection counteracts the therapeutic effects of folic acid antagonists such as methotrexate and similar medications by inhibiting the dihydrofolate reductase enzyme. It treats anemia by supplying the folic acid needed for red blood cell formation. It treats colorectal cancer by enhancing the therapeutic effects of another anticancer medication called 5-fluorouracil.
Interaction of Leucovorin Calcium 15mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications may interact with the effects of Leucovorin Calcium 15mg Injection and reduce its effectiveness by causing undesirable side effects. Especially inform your physician if you are taking medications for seizures.
More Information about Leucovorin Calcium 15mg Injection
- Keep the injection away from the reach of children and pets.
- If you forgot your dosing schedule, inform your healthcare professional immediately and reschedule the dosing
How to consume Leucovorin Calcium 15mg Injection
A trained physician or nurse in cancer chemotherapy will administer the drug to you. Your doctor will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. The medicine is administered either intravenously (into your vein) or intramuscularly (into your muscle) based on your disease condition.
Safety Advices
Pregnancy
There is a limited number of studies on the safety of Injection during pregnancy, and it is unknown whether the medicine can be given during pregnancy. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant.
Breast Feeding
Limited information is available on Injection safety during breastfeeding. Inform your physician if you are planning to breastfeed.
Lungs
It is unknown whether Injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
It is unknown whether Injection can be used in patients with liver disorders. Consult your doctor if you have any liver diseases before starting the treatment.
Alcohol
It is unknown whether it is safe to consume alcohol when taking Injection. Consult your doctor for more advice.
Driving
It does not affect the ability to drive or operate heavy machinery after taking Injection.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Allergic reactions
Common
- Diarrhea
- Nausea
- Vomiting
- Inflammmed and sore mouth
- Tiredness
Word of Advice
If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking these medicinal products. Inform your doctor if you have vomited immediately after receiving the injection. If you accidentally take too much Injection. contact your doctor and seek medical advice immediately. Do not stop taking this medicine unless your doctor tells you to. Your doctor will regularly do lab tests to check the effectiveness of the medicine.
FAQs
Q 1. Why is Leucovorin Calcium 15mg Injection given 24 hours after methotrexate?
Leucovorin Calcium 15mg Injection is usually administered 24 hours after methotrexate so that it does not interfere with the therapeutic effect of methotrexate. It can also be used in methotrexate overdose; it should be administered as soon as possible.
Q 2. Can Leucovorin Calcium 15mg Injection cause swelling?
Leucovorin Calcium 15mg Injection may cause allergic reactions like rash, low blood pressure, wheezing, shortness of breath, and swelling of the face or throat.
Q 3. Can Leucovorin Calcium 15mg Injection cause seizures?
There is no evidence that Leucovorin Calcium 15mg Injection cause seizures. But the medicine can affect the effect of seizure medication when administered concurrently. Inform your physician about all your medicines, including over-the-counter medications.
Fact Box
Molecule name: Leucovorin Calcium
Pharmacological class: Folic acid analogs
Therapeutic class:
1. Antineoplastics
2. Antidote
3. Rescue agents
Indications:
1. Methotrexate overdose and toxicity
2. Prevent the harmful effects of methotrexate or similar medication
3. Anemia
4. Colorectal cancer
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