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Introduction to Pivikto 200mg Tablet
The tablet Pivikto 200mg comprises the active ingredient Alpelisib, an anticancer agent belonging to the class of medications known as PI3K (phosphatidylinositol-3-kinase) inhibitors. It is employed in conjunction with other anticancer medications to address a specific type of breast cancer that has extended to nearby tissues or other parts of the body in postmenopausal women or in men whose cancer has worsened during or after specific prior treatments. Additionally, it is utilized in the treatment of individuals with certain types of PIK3CA-related overgrowth spectrum (PROS), a genetic condition leading to overgrowth and abnormalities in specific body tissues.
Avoid taking Pivikto 200mg if you have allergies to Alpelisib or any components in the medication. Notify your physician if you have elevated blood sugar levels or diabetes, bone disease, or exhibit symptoms of skin rash, blistering of the lips, eyes, or mouth, skin peeling, fever, or red skin. Report any signs of rash, itching, hives, breathlessness, shortness of breath, wheezing, cough, low blood pressure, or discoloration of lips, tongue, or skin to your doctor. It is not advisable for use in children and adolescents under 18 years of age.
Uses of Pivikto 200mg Tablet
- HER2- negative Breast cancer
Therapeutic Effects of Pivikto 200mg Tablet
Pivikto 200mg functions as a kinase inhibitor targeting phosphatidylinositol-3-kinase (PI3K), primarily inhibiting PI3K-alpha. In breast cancer cells, this medication’s inhibition of PI3K prompts an elevation in estrogen receptor transcription. These enzymes play a crucial role in the growth and multiplication of cancer cells. By impeding their action, Pivikto 200mg can mitigate cancer growth and spread, ultimately contributing to the destruction of cancer cells.
Interaction of Pivikto 200mg Tablet with other drugs
Notify your healthcare provider of all the medications you are currently using, encompassing prescription drugs, over-the-counter medications, nutritional and vitamin supplements, as well as herbal products. Some medications may interact with Pivikto 200mg, diminishing its effectiveness and potentially leading to undesirable side effects.
More Information about Pivikto 200mg Tablet
- Store the Pivikto 200mg at 20°C to 25°C
- Protect the medicine from light and excessive moisture.
- Keep the medicine out of reach of children and pets
- If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.
How to consume Pivikto 200mg Tablet
The dosage and duration of Pivikto 200mg will be determined by your doctor based on your disease condition and other relevant factors. Always adhere to your doctor’s prescription and take the medicine as directed. Consume the tablet at the same time, immediately after a meal. Do not break, chew, crush, or split the tablet; instead, swallow it whole with water. If swallowing the tablet proves challenging, follow your doctor’s advice on dissolving the tablets in a glass of water.
Safety Advices for Pivikto 200mg Tablet
Pregnancy
Do not take Pivikto 200mg if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for 1 week after the last dose.
Breast Feeding
Breastfeeding is not recommended in patients taking Pivikto 200mg because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
Liver
Pivikto 200mg is safe to use in patients with liver problems. There is no need for dose adjustments. Inform your physician if you have any liver disease before initiating the therapy.
Alcohol
It is not known whether it is safe to consume alcohol with Pivikto 200mg. Please consult your doctor.
Driving
Pivikto 200mg may alter your ability to drive and operate heavy machinery. The treatment may cause tiredness hence avoid activities after taking the medicine.
Side Effects of Pivikto 200mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Common
- Hair loss
- Decreased weight
- Decreased appetite
- Nausea, vomiting
- Tiredness
Serious
- Cellulitis
- Hyperglycemia
- Diarrhea
- Hypersensitivity reactions
- Pneumonitis
- Dehydration
- Angioedema
Word of Advice
Before the treatment, your doctor may prescribe medications to prevent nausea and vomiting. If you vomit after taking the tablet, proceed to take the next dose at the regular time. Women undergoing treatment should employ an effective form of birth control during the treatment period and for one week after the final dose. Male patients with female partners should also use effective birth control during treatment and for one week after the last dose. Inform your doctor about any existing kidney disease, lung issues, breathing problems, or diabetes. Refrain from breastfeeding during the course of treatment and for one week following the last dose. Your doctor may recommend periodic blood tests during the treatment to monitor any potential unwanted side effects.
FAQs
Q 1. Can a patient with kidney problems take Pivikto 200mg?
Pivikto 200mg should be cautiously taken if you have any kidney problems. Dose adjustments are necessary for patients with kidney diseases. Inform your doctor if you are on dialysis and have any kidney disorders.
Q 2. What if I overdose or take two doses of Pivikto 200mg?
If you unknowingly overdosed or took two doses of Pivikto 200mg, immediately inform your healthcare professional and seek medical advice.
Q 3. Should Pivikto 200mg be taken with or without food?
Pivikto 200mg comes as a tablet to take by mouth. It is usually taken immediately after the food. Take the tablets as prescribed by your doctor.
Q 4. Does Pivikto 200mg cause hair loss?
Thinning or loss of your hair will usually start within two to four weeks of your first dose of Pivikto 200mg. You may also have thinning or loss of eyelashes, eyebrows, and other body hair. Consult your doctor if you have excessive hair loss.
Fact Box of Pivikto 200mg Tablet
Molecule name: Alpelisib
Pharmacological class: PI3K Inhibitors
Therapeutic class: Antineoplastics
Indications: Breast Cancer
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